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A more important consideration, suggests Siegel, is whether the potential threat posed by THS adds significantly to the hazards of smoking and SHS exposure

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While dedicated research on the interactions between NRT and antidiabetic drugs are scarce, the capacity of nicotineand by extension, NRTto raise blood glucose levels, disrupt glucose homeostasis, and lead to insulin resistance could be taken into account (Natvig Norderhaug et al., 2005